Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTLYSKKDIVQQARNLA------KMISETEEVDFFKRAEAQINENDK---------VSTIVNQIKALQKQAVNLKHYEKHEA---LKQVEAKIDALQEELEEIPVIQEFRDSQMEVNDLLQLVAHTISNQVTNEIITSTGGDLLKGETGSKVKHSNNSCSL 2AVU Chain:E ((5-160)) -SIVQEARDIQLAMELITLGARLQMLESETQLSRGRLIKLYKELRGSPPPKGMLPFSTDWFMTWEQNVHASMFCNAWQFLLKTGLCNGVDAVIKAYRLYLEQCPQAEE--GPLLALTRAWTLVRFVESGLLQLSSCNCCGGNFITHAHQPVGSFACSLC--

General information: TITO was launched using: RESULT: Template: 2AVU.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain E - contact count / total energy / energy per contact / energy per residue : 503 -51220 -101.83 -371.16 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain E : 0.60 3D Compatibility (PKB) : -101.83 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.60 QMean score : 0.307

(partial model without unconserved sides chains): PDB file : Tito_2AVU.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2AVU-query.scw PDB file : Tito_Scwrl_2AVU.pdb: