Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDMLYWLLIAAVFIIAFIGLVYPVIPSVVFIVAGFVLYGFLFSFSPYSYMFWLVEAVFAAVLFAADYVSNLLGVKRFGGSKAAIWGSTIGLLIGPFVIPVAGIILGPFIGAVCAELIVHQKDLKSAFKIGLGSLIGFLTGVIAKGIIQLLMIGYFLWTVL 3F62 Chain:A ((18-125)) ---------GAMVETKCPNL------DIVTSSGEFHCSGCVEHMPEFSYMYWLAKDM--------KSDEDTKFIEHLGD----------GINEDETVRTTDG-------GITTLRKVLHVTDTNKFAHYRFTCVLTTLDGVSKKNIWL------------

General information: TITO was launched using: RESULT: Template: 3F62.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 484 -90137 -186.23 -834.60 target 2D structure prediction score : 0.06 Monomeric hydrophicity matching model chain A : 0.54 3D Compatibility (PKB) : -186.23 2D Compatibility (Sec. Struct. Predict.) : 0.06 1D Compatibility (Hydrophobicity) : 0.54 QMean score : 0.182

(partial model without unconserved sides chains): PDB file : Tito_3F62.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3F62-query.scw PDB file : Tito_Scwrl_3F62.pdb: