Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVSIRRSFEAYVDDMNIITVLIPAEQKE--IMTPPFRLETEITD-FPLAVREEYSLEAKYKYVCVSDHPVTFG-KIHCVRASSGHKTDLQIGAVIRTAAFDDEFYYDGELGAVYTA--DHTVFKVWAPAATSAAVKLSHPNK---SGRTFQMTRLEKGVYAVTVTG-----DLHGYEYLFCICNNSEWMETVDQYAKAVTVNGE----------KGVVLRPDQMKWTA----PLKPFSHPVDAVIYETHLRDFSIHENSGM---INKGKYLALTETDTQTANGSSSGLAYVKELGVTHVELLPVNDFAGVDEEKP---------LDAYNWGYNPLHFFAPEGSYASNPHDPQTRKTELKQMINTLHQHGLRVILDVVFNHVYKRENSPFEKTVPGYFFRHDECGMPSNGTGVGNDIASERRMARKFIADCVVYWLEEYNVDGFRFDLLGILDIDTVLYMKEKATKAKPGILLFGEGWDLATPL-PH-EQKAALANAPRMPGIGFFNDMFRDAVKGNTFHLKATGFALGNGESAQAVMHGIAGSSGWKALAPI-VPEPSQSINYVESHDNHTFWDKMSFALPQE---NDSRKRSRQRLAAAIILLAQGVPFIHSGQEFFRTKQG------------------------------VENSYQSSDSINQLDWDRRET------FKEDVHYIRRLISLRKAHPAFRLRSAADIQRHLECLT--------LKEHLIAYRLYDLDEVDEWKDIIVIHHASPDSVEWRLPN----DIPYRLLCDPSGFQEDP-------TEIKKTVAVNGIGTVILYLASDLKSFA 3FAW Chain:A ((37-814)) ---QVQLKDAQQTDLTSIQASFTTLD--KTEILKELKVTDKNQNAIQISDIT----LDTSKSLLIIKGDFNPKQGHFNISYNGNNV-----TTRQSWEFKDQLYAYSGNLGAVLNQDGSKVEASLWSPSADSVTMIIYDKDNQNRVVATTPLVKNNKGVWQTILDTKLGIKNYTGYYYLYEIKRGKDKVKILDPYAKSLAEWDSNTVNDDIKTAKAAFVNPSQLGPQNLSFAKIANFKGRQDAVIYEAHVRDFTSDQSLDGKLKNQLGTFAAFS-----------EKLDYLQKLGVTHIQLLPVLSYFYVNEMDKSRSTAYTSSDNNYNWGYDPQSYFALSGMYSEKPKDPSARIAELKQLIHDIHKRGMGVILDVVYNHTAK--TYLFEDIEPNYYHFMNEDGSPRESFG-GGRLGTTHAMSRRVLVDSIKYLTSEFKVDGFRFDMMGDHDAAAIELAYKEAKAINPNMIMIGEGWRTFQGDQGKPVKPADQDWMKSTDTVGVFSDDIRNSLKSGFPNEGTPAFITGGPQSLQGIFKNIKAQP-----GNFEADSPGDVVQYIAAHDNLTLHDVIAKSINKDPKVAEEDIHRRLRLGNVMILTSQGTAFIHSGQEYGRTKRLLNPDYMTKVSDDKLPNKATLIEAVKEYPYFIHDSYDSSDAINHFDWAAATDNNKHPISTKTQAYTAGLITLRRSTDAFRKLSKAEIDREVSLITEVGQGDIKEKDLVIAYQTIDSK----GDIYAVFVNADSKARNVLLGEKYKHLLKGQVIVDADQAGIKPISTPRGVHFEKDSLLIDPLTAIVIKVG-------

General information: TITO was launched using: RESULT: Template: 3FAW.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 4102 102398 24.96 151.93 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : 24.96 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.443

(partial model without unconserved sides chains): PDB file : Tito_3FAW.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3FAW-query.scw PDB file : Tito_Scwrl_3FAW.pdb: