Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTNNLKQRRIILDLAVTLDGFIEGKNGEVDWCIMD-PDMGFTDFLNQIDTILYGRKSFDLWGQYIPKNEDPDTEKELWKLVHSKKKYVFSRTQNEI-D----------------------NQAIFIND-NILEEVNKLKKNPG-KDIWLYGGASLITTFINLGLVDEFRLSIHPVVLGEGKP-LFIDV----KQRINLKMVNTRTFSSGVVQIVYHWNG 3ZPG Chain:A ((168-378)) ---STGMPYVRLKVASSLDGRTAMASGES--ITGSAARQDVQHWRAISGAVITGIDTVIADDCQLNVRSLH---NIDIETVAQPKRVILDRRGRLPLTAKILENPETVMVMGPYRQELADLGVIQLEIQPLKTLLQTLSKQYQIYDVLIEAGATLSSAFLQEGLIDEMISYVAPTLLGQSARAMFNADFEYMAQQLRFKLLDVIQLD-QDIRLRLIPT-

General information: TITO was launched using: RESULT: Template: 3ZPG.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 866 -14956 -17.27 -84.02 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : -17.27 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.482

(partial model without unconserved sides chains): PDB file : Tito_3ZPG.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3ZPG-query.scw PDB file : Tito_Scwrl_3ZPG.pdb: