Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRPLARLRGRRVVPQRSAGELDAMAAAGAVVAAALRAIRAAAAPGTSSLSLDEIA-ESVIRESGATPSFLGYHGYPASICASINDRVVHGIPSTAEVLAPGDLVSIDCGAVLDGWHGDAAITFGVGALSDADEALSEATRESLQAGIAAMVVGNRLTDVAHAIETGTRAAELRYGRSFGIVAGYGGHGIGRQMHMDPFLPNEGAPGRGPLLAAGSVLAIEPMLTLGTTKTVVLDDKWTVTTADGSRAAHWEHTVAVTDDGPRILTLG 2GU4 Chain:A ((5-249)) ---------------KTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEA------EGFSVVREYCGHGIGRGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMKDGWTVKTKDRSLSAQYEHTIVVTDNGCEILTL-

General information: TITO was launched using: RESULT: Template: 2GU4.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -120108 for 2122 contacts (-56.6/contact) + 2D Compatibility (PS) -26823 + (NN) -9131 + (LL) 1528 1D Compatibility (HY) -18000 + (ID) 4700 Total energy: -177234.0 ( -83.52 by residue) QMean score : 0.480

(partial model without unconserved sides chains): PDB file : Tito_2GU4.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2GU4-query.scw PDB file : Tito_Scwrl_2GU4.pdb: