Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence --MLSDNNFVSETLENVQYLLPGAKVIKLRGYSRAHKVYTIAKS-PVEKWKVAAGLSGSEIAILIRKGHWIGASIPAGGIVIDIDDSKQGELVKGLLDAQNFHCHC--IRTLMGGSLFLRITNMGKRKLNK 2M1M Chain:A ((1-107)) HEADVGGIFVKVSMDGAPY-LRKIDLRVYGGYSELLKALETMFKLTIGEYSEREGYKGSE-------------------YAPTYEDKDGDWMLVGDVPWDMFVTSCKRLRIMKGTEA----KGLGCGVGSH

General information: TITO was launched using: RESULT: Template: 2M1M.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 459 -35741 -77.87 -350.40 target 2D structure prediction score : 0.31 Monomeric hydrophicity matching model chain A : 0.60 3D Compatibility (PKB) : -77.87 2D Compatibility (Sec. Struct. Predict.) : 0.31 1D Compatibility (Hydrophobicity) : 0.60 QMean score : 0.218

(partial model without unconserved sides chains): PDB file : Tito_2M1M.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2M1M-query.scw PDB file : Tito_Scwrl_2M1M.pdb: