Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTKKRITFGLLVLMVCVILFVLYVQLRNKDSIPVQSSAIHPEEDRIFFIYSNPFIKESVLLSTSTGERFNRRTFKVADVPYIQTKSYASTDLVLLAEHEPFYYTLEKDVIKEHPLSDPFAFWYEGKDVTIEAYNVDTTGNEIHINDRKTKKEY-TLTLP--PLVTMGASDENFIYIIQS--MSIYVIDRKTEEMIETLSLASYADQFADSE--EFIVASS--DHKLTVIEKGTWKT-TYIAYPEDLEYADTVYYDKESGSFYVAYEDKEGGANLLEYGEDF-SI-HTYSLKFPYMEAK--FKGNLLYIVAQEEHKKGIGGYVGVFDIHSKEMLYQFDLPEEQVKVQDFVVVDNK 1L0Q Chain:A ((12-197)) -------------------------------------------------------------------------------------------------------------------------------------------DNISVIDVTSNKVTATIPVGSNPMGAVISPDGTKVYVANAHSNDVSIIDTATNNVIATVPAGSSPQGVAVSPDGKQVYVTNMASSTLSVIDTTSNTVAGTVKTGK---SPLGLALSPDGKKLYVTNNGDK---TVSVINTVTKAVINTVSVGRSPKGIAVTPDGTKVYVANF------DSMSISVIDTVTNSVIDTV------------------

General information: TITO was launched using: RESULT: Template: 1L0Q.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 922 -99944 -108.40 -584.46 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.61 3D Compatibility (PKB) : -108.40 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.61 QMean score : 0.453

(partial model without unconserved sides chains): PDB file : Tito_1L0Q.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1L0Q-query.scw PDB file : Tito_Scwrl_1L0Q.pdb: