Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKYHISMINIPAYGHVNPTLALVEKLCEKGHRVTYATTEEFAPAVQQAGGEALIYHTSLNID-PKQIREM-MEKNDAPLSLLKESLSILPQLEELYK-DDQPDLIIYDFVAL-AGKLFAEKLNVPVIKLCSSYAQNES-FQ--LGNE------DM-LKKIREAEAEFKAYLEQEKLPAVSF-E-Q-LAVPEALNIVFMPKSFQIQHETFDDRFCFVGPSL-GERKEKESLLIDKDDRPLMLISLGTAFNAWPEFYKMCIKAFRDSSWQVIMSVGKTIDPESLEDIPANFTIRQSVPQLEVLEKADLFISHGGMNSTMEAMNAGVPLVVIPQMYEQELTANRVDELGLGVYLPKEEVTVSSLQEAVQAVSSDQELLSRVKNMQKDVKEAGGAERAAAEIEAFMKKSAVPQ 3RSC Chain:A ((19-414)) -HMAHLLIVNVASHGLILPTLTVVTELVRRGHRVSYVTAGGFAEPVRAAGATVVPYQSEIIDADAAEVFGSDDLGVRPHLMYLRENVSVLRATAEALDGDV-PDLVLYDDFPFIAGQLLAARWRRPAVRLSA-AFASNEHYSFSQDMVTLAGTIDPLDLPVFRDT-LRD-LLA--EH-GLSRSVVDCWNHVEQLNLVFVPKAFQIAGDTFDDRFVFVGPCFDDRRFLGEWTRP-ADDLPVVLVSLGTTFNDRPGFFRDCARAFDGQPWHVVMTLGGQVDPAALGDLPPNVEAHRWVPHVKVLEQATVCVTHGGMGTLMEALYWGRPLVVVPQSFDVQPMARRVDQLGLGAVLPGEKADGDTLLAAVGAVAADPALLARVEAMRGHVRRAGGAARAADAVEAYLAR-----

General information: TITO was launched using: RESULT: Template: 3RSC.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2213 -287048 -129.71 -759.38 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain A : 0.77 3D Compatibility (PKB) : -129.71 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.656

(partial model without unconserved sides chains): PDB file : Tito_3RSC.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3RSC-query.scw PDB file : Tito_Scwrl_3RSC.pdb: