Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNKPIGVIDSGVGGLTVAKEIMR-QLPNETIYYLGDIGRCPYGPRPGEQVKQYTVEIARKLMEFDIKMLVIACNTATAVALEYLQKTLSIPVIGVIEPG--ARTAIMTTRNQNVLVLGTEGTIKSEAYRTHIKRINPHVEVHGVACPGFVPLVEQMRYSDPTITSIVIHQTLKRWRNSE----SDTVILGCTHYPLLYKPIYDYFGGK------KTVISSGLETAREVSALLTFSNEHASYTEHPDHRFFATGDPTHITNIIKEWLNLSVNVERISVND 2W4I Chain:A ((3-255)) ----IGVFDSGVGGFSVLKSLLKARLFDEIIYY-GDSARVPYGTKDPTTIKQFGLEALDFFKPHEIELLIVACNTASALALEEMQKYSKIPIVGVIEPSILAIKRQVEDKNAPILVLGTKATIQSNAYDNALKQ-QGYLNISHLATSLFVPLIEE------SILEGELLETCMHYYFTPLEILPEVIILGCTHFPLIAQKIEGYFMGHFALPTPPLLIHSGDAIVEYLQQKYALKNNACTF---PKVEFHASGDVIWLERQAKEWLKL-----------

General information: TITO was launched using: RESULT: Template: 2W4I.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -172300 for 2120 contacts (-81.3/contact) + 2D Compatibility (PS) -25308 + (NN) -4413 + (LL) 1480 1D Compatibility (HY) -22000 + (ID) 4600 Total energy: -227141.0 ( -107.14 by residue) QMean score : 0.505

(partial model without unconserved sides chains): PDB file : Tito_2W4I.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2W4I-query.scw PDB file : Tito_Scwrl_2W4I.pdb: