Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTNKITERITGHTELIGLIATPIRHSLSPTMHNEAFAKLGLDYVYLAF----EVGDKELKDVVQGFRAMNLRGWNVSMPNKTNIHKYLDKLSPAAELVGAVNTVVNDDGVLTGHITDGTGYMRALKEAGHDIIGKKMTICGAGGAATAICI--QAALDGVKEISIFNRKDDFYANAEKTVEKINSKTDCKAQLFDIEDHEQLRKEIAESVIFTNATGVGMKPFEGETLLPSADMLRPELIVSDVVYKPTKTRLLEIAEEQGCQTLNGLGMMLWQGAKAFEIWTHKEMPVDYIKEILF 2D5C Chain:B ((4-244)) ---------------FAVLGHPVAHSLSPAMHAFALESLGLEGSYEAWDTPLEALPGRLKEVRRAFRGVNL-----TLPLKEAALAHLDWVSPEAQRIGAVNTVLQVEGRLFGFNTDAPGFLEALKAGGIPLKGPALVLGAGGAGRAVAFALREAGL----EVWVWNRTPQ---RALALAEEFGLRA------VPLEKAREAR-------LLVNATRVGL----ASPL--PAELFPEEGAAVDLVYRPLWTRFLREAKAKGLKVQTGLPMLAWQGALAFRLWT--------------

General information: TITO was launched using: RESULT: Template: 2D5C.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -138555 for 2012 contacts (-68.9/contact) + 2D Compatibility (PS) -24712 + (NN) -6199 + (LL) 4572 1D Compatibility (HY) -14400 + (ID) 4200 Total energy: -183494.0 ( -91.20 by residue) QMean score : 0.565

(partial model without unconserved sides chains): PDB file : Tito_2D5C.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2D5C-query.scw PDB file : Tito_Scwrl_2D5C.pdb: