Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKIAAFDIGGTALKMGVVLPHGEIILTKSAEISGSDGDQILAEMKVFLAENTDVTGIAVSAPGYVNPKTGLITMGGAIRRFDNFNLKEWLEAETGLPVAIENDANCALLAEKWLGKGQDLDDFLCLTIGTGIGGGIFSNGELVRGGRFRAGEFGYMFSERPGAFRPGKYTLNETTTMLVLRRQYAELTGRPLEEITGEEIFANYDAHDAVSERLITEFYTGICTGLYNLIYLFDPTHIFIGGGITSRPTFIAELKHHMESFGL------RDTIIETATHKNQAGLLGAVYHFLQEENRHE 2GUP Chain:A ((4-291)) MTIATIDIGGTGIKFASLTPDGKILDKTSISTPE-NLEDLLAWLDQRL-SEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALS-SYQLPVHLENDANCVGLSELLAHP--ELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAP---AEKLNNWSQLASTGNMVRYVIEKSGH--TDWDGRKIYQEAAAGNILCQEAIERMNRNLAQGLLNIQYLIDPGVISLGGSISQNPDFIQGVKKAVEDFVDAYEEYTVAPVIQACTYHADANLYGALVNWLQEEKQ--

General information: TITO was launched using: RESULT: Template: 2GUP.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -211462 for 2366 contacts (-89.4/contact) + 2D Compatibility (PS) -30094 + (NN) -16521 + (LL) 496 1D Compatibility (HY) -18000 + (ID) 4900 Total energy: -280481.0 ( -118.55 by residue) QMean score : 0.553

(partial model without unconserved sides chains): PDB file : Tito_2GUP.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2GUP-query.scw PDB file : Tito_Scwrl_2GUP.pdb: