Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MANTYDLISQRIEAQRQKLIAIDIVAVASSLGLNLKQGSGGHLYWDEHDSFHIYPQTNTFRWWSRSMGTNTIDLVQVIQEELTGKKPSFRETVNFLETGQFESVTVTPVVREPFKHYLAPYEHHNFDLGRQYLKEERGLSDETIDFALASGSMSSATLKKGDYFEPVIIFKSFAEDGRMIGGSLQGIVENKVQHPERGRLKQIMKHSDGLAGFHLDVGTPKRLVFSEAPIDLLSYYELHKESLQNVRLVAMDGVKKGVISRYTADLLTDGQYSQTMPRESIRGAIDAINQTTRILKNN---PNMITIAVDNDEAGRNFIKELQEDGIPINVDLPPRKEHQSKMDWNNYLKQKKGLLKMPQTEGTQKAPEQVLEHEKMDRSQISSGSLEDDPQGSAKPVSKRDTFEQAVTSHPTFSYPLLQFSTEEAFVSNVRDGYHIASEEDIRNLNYYAPSLQQTANWYRDNLADRQVTYMLK--GDKEIKALQVSFAKDKFAHLTGIRPIGKGLSAEKLLDDFAKGRGSYPNLTLSNGFNDKIQVLPMIQELSQSKSF--VFTDLEEVQKMRNLKASHAIQS-NNRSLVVALKTIDDVTFPSSLLRGKKNLNDDLIQKAKENEVLGVLSEKDGNITVLSVNDKYIQDGG---QALKDMIKNGELEPLQMETIQRHVPHENAYPKDSDGDGLTDDEEIALGTNPFSSDSDGDGTPDNVEKANGTDPTNASDNEVTRQQEANKRDFTLSEMIKAKNTAALNQHLQDGIKQYFDSDTYKQYLEGMAHFNNYSPRNIQLIMSQFPEASMVASFQEWRKRNGSVKKGEKAIYIQAPVSVMKKDENGKPILNPETGEKETITYFKPVPVFDIKQVSPQEGKELNLPKAMGTIPE-----QLDKEYYQNVYRSLRDISQNNNKVPIRFRELGQEDGFYSPQTNEIVIKKGMSYERTLSTLIHEMAHSELHNKQSLTERFDGKLTRSTKELQAESIAYVVSSHLGFDTSQESFPYLA-SWSKEKDGLANLTAQ------LEIVQEEAKNLMERIDQQLSQYQTVTLNKETQQLTKQEMKKQTHPFYQSLAAAKTSRAQVTTQEKEASVKKDNRPTMP 3UGM Chain:A ((169-1048)) KPKVRELVAHIVALSQHP-------------------------------------------------------------AALGTVAVTYQHIITALAT-----------------------HEDIVGVGKQW-----------------SGARALEALLTDA--------------GELRGPPLQ---------LDTGQLVKIAKRG-GVTAMEAVHASRNALT----PLNL-TPAQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPAQVVAIASHDGGKQALETMQRLLPVLCQAHGLPPDQVVAIASNIGGKQALETVQRL-------LPVLCQAHGL--------TPDQVVAIASHGGGKQALETVQRLLPVLCQA--HGLTPDQVVAIASHDGGKQALETVQRLLPVLCQA--HGLTPDQVVAIASNG---GGKQALETVQRLLPVLCQA-----HGLTPDQVVAIASNGGKQALETVQRLLPVLCQAHGLTPDQVVAIASHDGGKQALETVQRLLPVLCQTHGLT-PAQVVAIASHDGGKQALETVQQLLPVLCQAHGLTPDQVVAIASNIGGKQALATVQRLL---PVLCQAHGLTPDQVVAIASNG-----GGKQALETVQRLLPVLCQAHGLTPDQVVAIASNGGGKQA-LETVQRLL------PVLCQAHGLTQVQVVAIASNI--------GGKQALETVQRLLPVLCQAHGLTP-----------------AQVVAIASH--DGGKQALETVQRL--LPVLCQAHGLTPDQVVAIASNGGGKQALETVQRLLPGLT-----------QEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNI-GGKQALETVQRLLPVLCQDHGLTLAQVVAIASNIG--------------GKQALETVQRLLPVLCQGLT----QDQVVAIASNIGGKQALETVQRLLPVLCQDHGLTPDQVVAIASNIGGKQALETVQRLLPVLCQDHGLTLDQVVAIASNGGKQALETVQ----------RLLPVLCQDHGLTPDQVVAIASNSG-----

General information: TITO was launched using: RESULT: Template: 3UGM.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) 278298 for 7020 contacts (39.6/contact) + 2D Compatibility (PS) -87221 + (NN) -21028 + (LL) 17180 1D Compatibility (HY) -21600 + (ID) 7550 Total energy: 158079.0 ( 22.52 by residue) QMean score : 0.170

(partial model without unconserved sides chains): PDB file : Tito_3UGM.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3UGM-query.scw PDB file : Tito_Scwrl_3UGM.pdb: