Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKLISWNIDSLNAALTSESTRALMSRQVIDTLVAEDADIIAIQETKLSAKGPTKKHLEVLETYFPEYDLVWRSSVEPA-RKGYAGTMFLYRKGLNPIVSFPEIDAPTTMDNEGRIITLELENCYITQVYTPNAGDGLKRLGDR-QIWDIKYAEYLATLDSQKPVLATGDYNVAHKEIDLANPSSNRRSAGFTDEERQGFTNLLAKGFTDTFRYLHGDVPNVYSWWAQRSRTSKINNTGWRIDYWLTSNRVADKITKSEMIHSGDRQDHTPIILEIEL 3G4T Chain:A ((4-251)) LKIISWNVNGL---------RAVHRKGFLKWFMEEKPDILCLQEIKAAPEQLPRK-LRHVEGY--------RSFFTPAERKGYSGVA-MYTK--VPPSSLREGFGVERFDTEGRIQIADFDDFLLYNIYFPNGKMSEERLKYKLEFYDAFLEDVNRERDSGRNVIICGDFNTAHREIDLARPKENSNVSGFLPVERAWIDKFIENGYVDTFRMFNSD-PGQYTWWSYRTRARE-RNVGWRLDYFFVNEEFKGKVKRSWILSDVMGSDHCPIGLEIE-

General information: TITO was launched using: RESULT: Template: 3G4T.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -49741 for 2003 contacts (-24.8/contact) + 2D Compatibility (PS) -26629 + (NN) -12443 + (LL) 1952 1D Compatibility (HY) -18400 + (ID) 4300 Total energy: -109561.0 ( -54.70 by residue) QMean score : 0.515

(partial model without unconserved sides chains): PDB file : Tito_3G4T.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3G4T-query.scw PDB file : Tito_Scwrl_3G4T.pdb: