Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MISVLFVCLGNICRSPMAEAIFRDLAAKKGLEGKI-KADSAGIGGWHIGNPPHEGTQEILRREGISFDGMLARQVSEQDLDDFDYIIAMDAENIGSLRSMAGFKNTSHIKRLLDY----------VEDSDLADVPDPYYTGNFEEVCQLIKTGCEQLLASIQKEKQL 1D1Q Chain:A ((8-154)) -ISVAFIALGNFCRSPMAEAIFKHEVEKANLENRFNKIDSFGTSNYHVGESPDHRTVSICKQHGVKINHK-GKQIKTKHFDEYDYIIGMDESNINNLKKIQPEGSKAKVCLFGDWNTNDGTVQTIIEDPWYGDIQDFEY--NFKQITYFSK----------------

General information: TITO was launched using: RESULT: Template: 1D1Q.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 713 -69554 -97.55 -511.43 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.78 3D Compatibility (PKB) : -97.55 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.78 QMean score : 0.540

(partial model without unconserved sides chains): PDB file : Tito_1D1Q.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1D1Q-query.scw PDB file : Tito_Scwrl_1D1Q.pdb: