Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MERKTVLVIADLGGCPPHMFYKSAAEKYNLVSFIPRPFAITASHAALIEKYSVAVIKDKDYFKSLADFEHPDSIYWAHEDHDKPEEEVVEEIVKVAGMFAVDAITTNNELFIAPMAKACERLGLRG-AGVQAAENARDKNKMRAAF-NRAGVKSIKNKRVTTLEDFRAALQEIGTPLILKPTYLASSIGVTLIKEMETAEAEFNRVNEYLKSINVPKAVTFEAPFIAEEFLQ-GEYDDWYETSGYSDYISIEGIMA-DGEYFPVAIHDKTPQIGFTETSHITPSILDDDAKRKIVEAAKKANEGLGLENCATHTEIKLMKNREAGLIESAARFAGWNMIPNIKKVFGVDMAQLLLDVLCFGKEADLPKGLLEQEPCYVADCHLYPQHFKENGQLPETAVDFVIESIDIPDGVLKGDTEIVSFSAAEAGTSVDLRLFEAFNSIAAFELKGSNSGDVAESIKQIQQQAKLTAKYALPV 1KJQ Chain:A ((10-390)) -AATRVMLLGS-G-ELGKEVAIECQRL-GVE-----VIAVDRYADAPAMH-------------------VAHRSHVINM---LDGDALRRVV----ELEKPHYIVPEIEAIATDMLIQLEEEGLNVVPCARATKLTMNREGIRRLAAEELQLPTSTYRFADSESLFREAVADIGYPCIVKPVMS---KGQTFIRSAEQLAQAWKYAQQGGR---AGA-----GRVIVEGVVKFDFE------------ITLLTVSAVDGVHFCAPVGHRQEDG--DYRESWQPQQMSPLALERAQEIARKVVLALGG-YGLFGVELFVCG-DEVIFSEVSPRPHDTGMVTLI--SQDLSEFALHVRAFLGLPVGGIRQY--------------GPAAS-AVILP-QLTSQNVTF--DNVQNAV--GADLQIRLF---GKPEI--DGSRRLGVALAT--AESVVDAIERAKHAAGQVKVQ-------

General information: TITO was launched using: RESULT: Template: 1KJQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2264 -28557 -12.61 -76.36 target 2D structure prediction score : 0.53 Monomeric hydrophicity matching model chain A : 0.61 3D Compatibility (PKB) : -12.61 2D Compatibility (Sec. Struct. Predict.) : 0.53 1D Compatibility (Hydrophobicity) : 0.61 QMean score : 0.392

(partial model without unconserved sides chains): PDB file : Tito_1KJQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1KJQ-query.scw PDB file : Tito_Scwrl_1KJQ.pdb: