Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTAHDQELRRRAYEEVEKKEPIANSDPHRQHFHIMPPVGLLNDPNGVIYWKGSYHVFFQWQPFQTGHGAKFWGHYTTQDVVNWKREEIALAPSDWFDKNGCYSGSAVTK-D-------DRLYLFYTGNVRDQDGNRETYQCLAVSDD-GLSFEKKG-VVARLPE----------GYTAHFRDPKVWEH--EGTWYMVIGAQTENLKGQAVLFASDNLTEWRFLGPITGAGFNGLDDFGYMWECPDLFSLQ-----GSDVLIVSPQGLEADGFRYQNVYQSGYFVGRLDYNKPELKHG--EFTELDQGFDFYAPQTLED---DQGRRILFAWMAVPDQDEGSHPT-IDCHWIHCMTLPRQLTLS---GQ--KLIQQPLPELKAMRRNEKKIH-INMHGSSGALPVEKPERTEILLE-DIHTESGFSISIRGT------ATFSFHKDEGIVTLERKSFDG-KRT-----E-ARHCRI-KDLHTVHMFLDASSVEIFINNGEEVLSARYFPFPGNHEVTASATGK--SEMNVGIWTLM 4FFH Chain:A ((2-479)) -----------------------------AVYHMTPPSGWLCNPQRPVTTHGAYQLYYLHSDQNN-GPG-GWDHASTTDGVAFTHHGTVMPLRP---DFPVWSGSAVVDTANTAGFGAGAVVALATQPTDG--VRKYQEQYLYWSTDGGFTFTALPDPVIVNTDGRAATTPAEIENAEWFRDPKIHWDTARGEWVCVIGRL-----RYAAFYTSPNLRDWTLRRNFDYP-----NHALGGIECPDLFEITADDGTRHWVLAASMDAYGI-----GLPMTYAYWTGTWDGE--QFHADDLTPQWLDWGWDWYAAVTWPSIDAPETKRLAIAWMNNWKYAARDVPTDASDGYNGQNSIVRELRLARQPGGWYTLLSTPVAALTNYVTATTTLPDRTVD--GSAVLPWNGRAYEIELDIAWDTATNVGISVGRSPDGTRHTNIGKY--GADLYVDRGPSDLAGYSLAPYSRAAAPIDPGARSVHLRILVDTQSVEVFVNAGHTVLSQQVHFAEGDTGISLYTDGGPAHFTGIVVREIG

General information: TITO was launched using: RESULT: Template: 4FFH.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2250 -8935 -3.97 -21.17 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : -3.97 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.461

(partial model without unconserved sides chains): PDB file : Tito_4FFH.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4FFH-query.scw PDB file : Tito_Scwrl_4FFH.pdb: