Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIKIKRGLDLPISGAPEQRIEAARPVRSVALIGFDYHGMKPTMAVQVGDRVKLGQVLFTDKKNPSVSYTAPGAGVVSAIHRGEKRVLQSVVIDLDGDEQLEFARYPADKLATLSAEQVRDNLLQSGLWTALRTRPFSKVPDPESSPSSIFVTAIDTQPLAADPQVVIAEQGEAFQAGLTVLGRLARVFLCKAEGVSLPGEALSGVTAQAFSGPHPAGLPGTHIHFLDPVGAGKSVWNLNYQDVIAIGKLFTTGQLWTERVIALAGPVVEKPRLVRTRLGANLDELAAGQLQPGNNRLISGSVLGGRTAHGAYAYLGRYHLQLSCLKEGDQREFLHYLRAGVEKHSLLNVFVSRLLGGKRFAFTTSTNGSPRAMVPVGNYEAVMPLDILPTQLLRYLIVGDTEMAQKLGALELDEEDLALCSYVCAGKYEYGPILRDNLARIEQEG 4TXD Chain:A ((21-369)) KRDVLAELGL------GDLRPYLRSIGDKDRIFPKAHRIEVVFLVRAANYLLLRTEGAGTINMTTLEYSG-GAMEVPVIQ-------PQKLMAVTRRQMLQLLREYRDSLDEVSKRWLVQEVIGKAKDLGFKKV---------SEEWNCTIQGMD-----------------GFCPHCTIFG-----------------AALTEQHNEKFGGL-SIGIK-TRVRF-DPAFATQRRITPETHNKVTEGHLSMTGQALFSEVHVEPGTVF----IGRAELV----DLTEPELVATLYSLATLRELGGRS--GIY---------------------------GTVRVEILGVKAGKYASTTAYDLAAENAGK--------GYEEVKKNLKERLEKLGFTPVDNSKLLAAVD----HKDPNGLFKDLWRSSIDFAEKMVKWVEELKGGG

General information: TITO was launched using: RESULT: Template: 4TXD.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -71969 for 2782 contacts (-25.9/contact) + 2D Compatibility (PS) -34939 + (NN) 4067 + (LL) 6564 1D Compatibility (HY) -11200 + (ID) 3100 Total energy: -110577.0 ( -39.75 by residue) QMean score : 0.202

(partial model without unconserved sides chains): PDB file : Tito_4TXD.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4TXD-query.scw PDB file : Tito_Scwrl_4TXD.pdb: