Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -MLPINRQQHILKWL-KEEGSLRISDI-SARFGVSEMTVYRDVNQLVQSNQVIKTAGGITL----P-VRTPQTDHM---CSYCLKPVNQAHSVQLITVNQDIEQLCCAHCAFLRYADKTEE-------VSHLICRDFLLQTTVSAGSAYFVVNA-ELNLHCCQPQAIPFATLDHAERF--QKGFGGA-VCTFDQALEDMLQDRKKRCTCTKK 3P06 Chain:A ((1-194)) NGVELSAVGVLLPVLMDSGRRISGGAFMAVKGDLSEHIKNP------KNTRIAQTVAGGTIYGLSEMVNIDEAEKLPIKGAITVLPVVQATATSILVPDNQPQLAFNSWEAAACAADTLESQQTPFLMVTGAVESGNLSPNLLAVQKQLLVAKPAGIGLAANSDRALKVVTLEQLRQVVGDKPWRKPMV-TFSSG--------KNVAQA---

General information: TITO was launched using: RESULT: Template: 3P06.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 931 -105986 -113.84 -616.20 target 2D structure prediction score : 0.44 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : -113.84 2D Compatibility (Sec. Struct. Predict.) : 0.44 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.171

(partial model without unconserved sides chains): PDB file : Tito_3P06.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3P06-query.scw PDB file : Tito_Scwrl_3P06.pdb: