Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSSSSQFKQLEKLGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHENIVRLYDVIHTENKLTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMIT-GKPLFPGTNDEEQLKLIFDIMGTPNESLWPSVTKLPKYNPNIQQRPPR-DLRQVLQPHTKEPLDGNLMDFLHGLLQLNPDMRLSAKQALHHPWFAEYYHHAS 4AU8 Chain:A ((5-293)) ---SQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRV--------PSSALREICLLKELKHKNIVRLHDVLH---KLTLVFEFCDQDLKKYFDSC-----NGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVR--SAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKP-YPMYPATTSLVNVV-----PKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDF-----

General information: TITO was launched using: RESULT: Template: 4AU8.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -162635 for 2234 contacts (-72.8/contact) + 2D Compatibility (PS) -29096 + (NN) -14872 + (LL) 1036 1D Compatibility (HY) -32800 + (ID) 8200 Total energy: -246567.0 ( -110.37 by residue) QMean score : 0.496

(partial model without unconserved sides chains): PDB file : Tito_4AU8.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4AU8-query.scw PDB file : Tito_Scwrl_4AU8.pdb: