Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTVYHFVGIKGTGMSPLAQILHDNGYTVQGSDIEKFIFTQTALEKRNITILPFSAENIKPGMTVIAGNAFPDTHPEIEKAMSEGIPVIRYHKFLGDYMK--KFTSVAVTGAHGKTSTTGLLAHVIQNAKPTSFLIGDGTGQ-GN---E------NSEYFVFEACEY-RRH----FLSYQPDYAIMTNIDFDHPDYFSSIDDVFDAFQEMALQVNK--GIIACGDDEHLPKIHANV---PVVYYGTGE-ENDFQARNIVKSTEGTTFDVFVRNTFYDTFYIPAYGHHNVLNSLAVIALCHYEEIDSSIIKHALKSFGGVKRRFNEKQ-LGDQVLIDD-YAHHPTEIKVTIEAARQKYPDREIVAVFQPHTFT-RTQQFLDEFAESLS--GADCVYLCDIFGSARENAGKLTIGDLQGKIHNAKLI--EEDDTSVL--K--AHDKAVLIFMGAGDIQKYMRAYENVMA 1GG4 Chain:A ((60-444)) ----------------------------------------------------------GGAGALLVSRPLDIDLPQLIVK-D---TRLAFGELAAWVRQQVPARVVALTGSSGKTSVKEMTAAILSQCGN-TLYTAGNLNNDIGVPMTLLRLTPEYDYAVIELGANHQGEIAWTVSLTRPEAALVNNLA--------SLAGVAKAKGEIFSGLPENGIAIMNADNNDWLNWQSVIGSRKVWRFSPNAANSDFTATNIHVTSHGTEFTLQTP-TGSVDVLLPLPGRHNIANALAAAALSMSVGATLDAIKAGLANLKAVPGRLFPIQLAENQLLLDDSYNANVGSMTAAVQVLAEM-PGYRVLVVGDMAELGAESEACHVQVGEAAKAAGIDRVLSVGKQS-H----------AISTASGVGEHFADKTALITRLKLLIAEQQVITILVKGSRSAAM-EEVVR----

General information: TITO was launched using: RESULT: Template: 1GG4.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1877 -30811 -16.42 -89.83 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -16.42 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.449

(partial model without unconserved sides chains): PDB file : Tito_1GG4.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1GG4-query.scw PDB file : Tito_Scwrl_1GG4.pdb: