Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRMRHKPWADDFLAENADIAISNPADYKGKWNTVFGNDNPIHIEVGTGKGQFISGMAKQNPDINYIGIELFKSVIVTAVQKVKDSEAQNVKLLNIDADTLTDVFEPGEVKRVYLNFSDPWPKKRHEKRRLTYSHFLKKYEEVMGKGGSIHFKTDNRGLFEYSLKSFSEYGLLLTYVSLDLHNSNLEGNIMTEYEEKFSALGQPIYRAEVEWRT 3E05 Chain:A ((41-167)) --------------------------------------DLVMWDIGAGSASVSIEASNLMPNGRIFALERNPQYLGFIRDNLKKFVARNVTLVEAFAPEGL--DDLPDPDRVFIGGSGGM-----------LEEIIDAVDRRLKSEGVIVLNAVTLDTLTKAVEFLEDHGYMVEV--------------------------------------

General information: TITO was launched using: RESULT: Template: 3E05.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 595 -65223 -109.62 -525.99 target 2D structure prediction score : 0.73 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -109.62 2D Compatibility (Sec. Struct. Predict.) : 0.73 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.601

(partial model without unconserved sides chains): PDB file : Tito_3E05.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3E05-query.scw PDB file : Tito_Scwrl_3E05.pdb: