Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKIAVINGGTRS--GGNTDVLAEKAVQGF-------DAEHIYLQKYPIQPIEDLRHAQG------------GFRP---VQDDYDSIIERILQCHILIFATPIYWFGMSGTLKLFIDRWSQTLRDPRFP--DFKQQMSVKQAYVIAVGGDNPKIK----GLPLIQQFEHIFHFMGMSFKGYVLGEGNRPGDILRDHQALSAASRLLKRSDAI 3W7A Chain:A ((2-185)) TKVLFITANPNSAEGSFGMAVGEAFIEAYKNEHPQDEVVTIDLFNTTVP-AIDADVFAAWGKFAAGEGFEALTEVQQQKVAAMNTNLETFMNADRYVFVTPMWNFSYPPVVKAYLDNVAIAGKTFKYTENGPVGLLEGKKALHIQATGGVYSEGAYAAVDFGRNHLKTVLGFVGVNDTEYIAVEG--------------------------

General information: TITO was launched using: RESULT: Template: 3W7A.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 576 -27799 -48.26 -180.51 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : -48.26 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.483

(partial model without unconserved sides chains): PDB file : Tito_3W7A.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3W7A-query.scw PDB file : Tito_Scwrl_3W7A.pdb: