Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTIDEIYQMYMNDVYRFLLSMTK---DKHLAEDLLQETFMRAYIHIHSYDH---SKVKPWLFQVARNAFIDYVRKHKKEVTISD-------D-----------LI--G-----------------------------SL--------FQ--NAVQSPAHQVEIKEV---LTGYMSELPDNYREALTLYYLKELNYKEASHIMNISEANFKSVLFRARQRLKALYNRGVNDE 1RP3 Chain:A ((9-234)) IEREELILKYLPLVKAIATNIKKHLPEDVDIRDLISYGVIGLIKAVDNLSTENPKRAEAYIKLRIKGAIYDYLRSLDFGSRQVREKERRIKEVVEKLKEKLGREPTDEEVAKELGISTEELFKTLDKINFSYILSLEEVFRDFARDYSELIPSSTNVEEEVIKRELTEKVKEAVSKLPEREKLVIQLIFYEELPAKEVAKILETSVSRVSQLKAKALERLREMLSN-----

General information: TITO was launched using: RESULT: Template: 1RP3.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 439 -61693 -140.53 -390.46 target 2D structure prediction score : 0.74 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -140.53 2D Compatibility (Sec. Struct. Predict.) : 0.74 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.567

(partial model without unconserved sides chains): PDB file : Tito_1RP3.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1RP3-query.scw PDB file : Tito_Scwrl_1RP3.pdb: