Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNEKNIKHSQNFITSKHNIDKIMTNIRLNEHDNIFEIGSGKGHFTLELVQRCNFVTAIEIDHKLCKTTENKLVDH-DNFQVLNKDILQFKFPK-----NQSYKIFGNIPYNISTDIIRKIVFDSI-ADEIYLIVEYGFAKRLLN--T---KRSLALFLMAEVDISILSMVPREYFHPKPKVNSSLIRLNRKKS-RISHKDKQKYNYFVMKWVNKE---YKKIFTKNQFNNSLKHAGI---DDLNNISFEQFLSLFNSYKLFNK 1QYR Chain:A ((17-267)) ---------QNFLNDQFVIDSIVSAINPQKGQAMVEIGPGLAALTEPVGERLDQLTVIELDRDLAARLQTHP-FLGPKLTIYQQDAMTFNFGELAEKMGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRLSVMAQYYCNVIPVLEVPPSAFTPPPKVDSAVVRLVPHATMPHPVKDVRVLSRITTEAFNQRRKTIRNSLGNLFSVEVLTGMGIDPAMRAENISVAQYCQMANYLAEN--

General information: TITO was launched using: RESULT: Template: 1QYR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1102 -19025 -17.26 -82.00 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : -17.26 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.595

(partial model without unconserved sides chains): PDB file : Tito_1QYR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1QYR-query.scw PDB file : Tito_Scwrl_1QYR.pdb: