Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSKRTAFVMGASQGIGKAIALKLADQHFSLVINSRNLDNIESVKEDILAKHPEASVIVLAGDMSDQHTRAGIFQKIESQCGRLDVLINNIPGGAPDTFDNCNIEDMTATFTQKTVAYIDAIKRASSLMKQNEFGRIINIVGNLWKEPGANMFTNSMMNAALINASKNISIQLAPHNITVNCLNPGFIATDRYHQFVENVMKKNSISKQKAEEQIASGIPMKRVGSAEETAALAAFLASEEASYITGQQISADGGSMKSI 3GED Chain:A ((2-232)) --NRGVIVTGGGHGIGKQICLDFLEAGDKVCFIDIDEKRSADFAKE------RPNLFYFHGDVADPLTLKKFVEYAMEKLQRIDVLVNNACRGSKGILSSLLYEEFDYILSVGLKAPYELSRLCRDELIKN-KGRIINIASTRAFQSEPDSEAYASAKGGIVALTHALAMSLGP-DVLVNCIAPGWINVT---EFTQE---------------DCAAIPAGKVGTPKDISNMVLFLCQQ--DFITGETIIVDGGMSKR-

General information: TITO was launched using: RESULT: Template: 3GED.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1239 -132722 -107.12 -582.11 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain A : 0.74 3D Compatibility (PKB) : -107.12 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.74 QMean score : 0.487

(partial model without unconserved sides chains): PDB file : Tito_3GED.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3GED-query.scw PDB file : Tito_Scwrl_3GED.pdb: