Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSEKKNIYPNKEGCPVEFTLDVIGGKWKGILFYHMIDGKKRFNEFRRICPSITQRMLTLQLRELEADGIVHREVYHQVPPKVEYSLTEFGRTLEPIVLQMKEWGESNRDVLESYRSNGLVKDQQK 1Z7U Chain:A ((8-109)) -----------KQTSINLALSTINGKWKLSLMDELFQGTKRNGELMRALDGITQRVLTDRLREMEKDGLVHRESFNELPPRVEYTLTPEGYALYDALSSLCHWGETFAQKKAR------------

General information: TITO was launched using: RESULT: Template: 1Z7U.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 282 -41431 -146.92 -406.19 target 2D structure prediction score : 0.49 Monomeric hydrophicity matching model chain A : 0.77 3D Compatibility (PKB) : -146.92 2D Compatibility (Sec. Struct. Predict.) : 0.49 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.433

(partial model without unconserved sides chains): PDB file : Tito_1Z7U.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1Z7U-query.scw PDB file : Tito_Scwrl_1Z7U.pdb: