Modeling by threading (Tito software)
Unconserved sides chains calculation (Scwrl software)
Evaluation (QMean software)
Input alignment information:
| Query sequence | MDSRAQLWGLALNKRRATLPHPGGSTNLKADPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDT-------KLWIIMEYLGGGSALDLLEPG--PLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQ-SAYDSKADIWSLGITAIELARGEPPHSELHPMKVLFLI---PKNNPPTLEGNYSKPLKEFVEACLNKEPSFRPTAKELLKHKFILRNAKKTSYLTELIDRYKRWKAEQSHDDSSSEDSDAETDGQASGGSDSGDWIFTIREKDPKNLENGALQPSDLDRNKMKDIPKRPFSQCLSTIISPLFAELKEKSQACGGNLGSIEELRGAIYLAEEACPGISDTMVAQLVQRLQRYSLSGGGTSSH |
| 1ZY4 Chain:A ((8-290)) | -----------------------------------FEEIAVLGQGAFGQVVKARNALDSRYYAIKKIRH--TEEKLSTILSEVMLLASLNHQYVVRYYAAWLERRNFVKKKSTLFIQMEYCENGTLYDLIHSENLNQQRDEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFIDESRNVKIGDFGLAKNVHR-----------AMYVATEVLDGTGHYNEKIDMYSLGIIFFEMIY--PFSTGMERVNILKKLRSVSIEFPPDFDDNKMKVEKKIIRLLIDHDPNKRPGARTLLNSGWLPVK---------------------------------------------------------------------------------------------------------------------------------------------------------- |
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General information:
TITO was launched using:
| RESULT:
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Template: 1ZY4.pdb
Alignment : align.pir
Tito was launched with SMD and SCWRL
Tito text output
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3D Compatibility (PKB) -106096 for 1792 contacts (-59.2/contact) +
2D Compatibility (PS) -26196 + (NN) -15364 + (LL) 9600
1D Compatibility (HY) -25600 + (ID) 3600
Total energy: -167256.0 ( -93.33 by residue)
QMean score : 0.264
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