Modeling by threading (Tito software)
Unconserved sides chains calculation (Scwrl software)
Evaluation (QMean software)
Input alignment information:
| Query sequence | MDAPWGAGERWLHGAAVDRSGVSLG-PPPTPQVNQGTLGPQVAPVAAGEVVKTAGGVCKFSGQRLSWWQAQESCEQQFGHLALQPPDGVLASRLRDP--VWVGQREAPLRRPPQRRARTTAVLVFDERTADRAARLRSPLPELAALTACTHVQWDCASPDPAALFSVAAPALPNA---LQLRAFAEPGGVVRAALVVRGQHAPFLAAFRAD-----GRWHHVCATWEQRGGRWALFSDGRRRAGAR----GLGAGHPVPSGG--------ILVLGQDQDSLGGGFSVRHALSGNLTDFHLWARALSPAQLHRARACAPPSEGLLFRWDPGALDVTPSLLPT------VWVRLLCPVPSEECPTWNP---GPRSEG---SELCLEPQPFLCCYRTEPYRRLQDAQSWPGQDVIS----RVNALANDIVLLPDPLSEVHGALSPAEASSFLGL-LEHVLAMEMA---PLGPAALL--AVVRFLKRVVALGAGDPELLL----TGPWEQLSQGVVSVASLVLEEQVADTWLSL------REVIGGPMALVASVQRLAPLLSTSM------------TSERPRMRIQHRHAGLSGVTVIHSWFTSRVFQHTLEGPDLEPQAPASSEEANRVQRFLSTQVGSAIISSEVWDVTGEV---NVAMTFHLQHRAQSPLFP-PHPPSPYTGGAWATTGCSVAALYLD------STACFCNHSTSFAILLQIYEVQRGPEEESLLRTL-SFVGCGVSFCALTTTFLLFLVAGVP--KSERTTVHKNLTF--SLASAEGFLMTSEWAKANEVACVAVTVAMHFLFLVAFSWMLVEGLLLWRKV-VAVSMH--------PGPGMRLYHATGWGVPVGIVAVTLAMLPHDYVAP-------------GHCWLNVHTNAIWAFV-GPVLFVL-----TANTCILARVVMITVSSARRRARMLSPQ--------PCLQQQIWTQIWA--TVKPVLVLLPVLGLTWLAGILVH---LSPAWAYAAVGLNSIQGLYIFLVYAACNEEVRSALQRMAEKKVAEVLRALG----------VWGGAAKEHSLPFSVLPLFLPPKPSTPRHPLKAPA------------------------------------------------------- |
| 4M8O Chain:A ((31-1186)) | ----ALSAQQLLNASKIDDIDSMMGFERYVPPQYNGRFDAKDIDQIPG----RVGWLTNMHATLVSQEVTTNQGISGVDFYFLDEEGGSFKSTVVYDPYFFIACNDESRVNDVEELVKKYLESCLKSLQIIRKEDLTMDNHLLGLQKTLIKLSFVNSNQLFEARKLLRPILQDNANNNVQRNIYNVKVDAKHLIEDIREYDVPYHVRVSIDKDIRVGKWYKVT----QQG----FIEDTRKIAFADPVVMAFAIATTKPPLKFPDSAVDQIMMISYMIDGEGFLITNREIISEDIEDFEYTPKPEYPGFFTIFNE--NDEVALLQRFFEHIRDVRPTVISTFNGDFFDWPFIHNRSKIHGLDMFDEIGFAPDAEGEYKSSYCSHMDCFRWVKRDSYLPQGSQGLKAVTQSKLGYNPIELDPELMTPYAFEKPQHLSEYSVSDAVATYYLYMKYVHPFIFSLCTIIPLNPDETLRKGTGTLCEMLLMVQAYQHNILLPNKHTDPIERFYDGHLLESETYVGGHVESLEAGVFRSDLKNEFKIDPSAIDELLQELPEALKFSVEVENKSSVDKVTNFEEIKNQITQKLLELKENNIRNE--LPLIYHVDV--ASMYPNIMTTNRLQPDSIKAERDCASCTCARKLKWAWRGEFFPSKMDEYNMIKRALQNETFPNKNKFSKKKVLTFDELSYADQVIHIKKRLTEYSRKVYHRVKVSEIVEREAIVCQR--ENPFYVDTVKSFRDRRYEFKGLAKTWKGNLSKIDPSDKHARDEAKKMIVLYDSLQLAHKVILNSFYGYVMRKGSRWYSMEMAGITCLTGATIIQMARALVERVGRPLELDTDGIWCILPKSFPETYFFTLENGKKLYLSYPCSMLNYRVHQKFTNHQYQELKDPLNYIYETHSENTIFFEVDGPYKAMILPSSKEEGKGIKKRYAVFNEDGSLAELKGFELKRRGELQLIKNFQSDIFKVFLEGDTLEGCYSAVASVCNRWLDVLDSHGLMLEDEDLVSLICENRSMS-KTLKEYEGQKSTSITTARRLGDFLGEDMVKDKGLQCKYIISSKPFNAPVTERAIPVAIFSADIPIKRSFLRRWTLDPSLEDLDIRTIIDWGYYRERLGSAIQKIITIPAALQGVSNPVPRVEHPDWLKRKIAT |
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General information:
TITO was launched using:
| RESULT:
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Template: 4M8O.pdb
Alignment : align.pir
Tito was launched with SMD and SCWRL
Tito text output
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3D Compatibility (PKB) -249913 for 6693 contacts (-37.3/contact) +
2D Compatibility (PS) -96743 + (NN) -9406 + (LL) 1656
1D Compatibility (HY) -21600 + (ID) 7200
Total energy: -383206.0 ( -57.25 by residue)
QMean score : 0.058
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