Modeling by threading (Tito software)
Unconserved sides chains calculation (Scwrl software)
Evaluation (QMean software)
Input alignment information:
| Query sequence | MKPKHYPDTISSPDFSSLEKEIIKFWQENKIFEQSVEKRSKDNCFVFYDGPPFANGLPHYGHLLTGFIKDAFARYQTMLQKKVERRFGWDCHGLPAEMGAEKELGISGRT---EIEKFGIEKF----NNYCRTSVMKFSSEWEKYVNRQARWVDFHNDYKTMD--RSFMESVIWAFKQLYDKGLVYESVRVVPYSWACETPLSNFETRLDTAYRKK-TSKAVTVAFELLENPQQFKQKCKLLAWTTTPWTLPSNLALAIGKDIEYCAVSVHSSVSFQHVTLESREKETWIPLSRTGMTEEGTETVTEDNEVSLVNNEIYIFAEDYLEKFIGHCEQNNIPYENCNTKLKADDLAGLSYKPLFNYFKGTKNAFRVFIADYVTGEDGTGVVHTAPGFGEEDFY----------LCQSHDIPA---ICPID--------NSG-------------------------RFTAEVSDLTGIHVFDTNDAIIKKLKEQGNWFKTEQYIHNYPHCWRTD-TPLIYRAMPSWYVAVT--KFKERMIELNKRVNWIPTHIRDGQFGKWLERAHDWSISRNRFWGTPIPI---WKSDNARYPRVDVY-GSIAELERDFNVKVNDLHRPFIDSLTRPNPDDPTGKS--IMRRVPDVFDCWFESGSVPFA------QVHYPFEN----KEWFESNFPADFITEYIAQTRGWFYTLFVLSTALF-DSEPFKNCICHGVVLDVKGQKLSKRLNNYADPMEVFDKYGSDALRFLMLSGSIVCGGNLFLNKEGSSIRDVLKNVMKPIWNSYHFFTMYANADGIKAEVCKDYKSTIDSYMIFKCFEAVESIQASMSNYNSQEACKILI-DFFEVLNNWYIRRSRERFWKSNLDQDKTDAYNVLYTVFYYILRAAVPLLPLITETIWQGLKYKEISVHLADFPQLER--YDSELIAKMDLVREICNSALSIRNTFNIRVRQPLGSMTVYHQSSCSFLESKPLSVVIPKFSPVIPMRDTGTQKEKKWSNAEMKTSMNEYQEMIKDEVNVKELKLVNSLEGIASLELKLNFPMLGKRIPDKVKKLVQYVKEGKWKQVDNEQVFLGNESESYIIEKDEYELLLKTNSEYSSVFGDNKGIVILNTALDDALVLEGLARDVVRLIQEARKQADFHISDRIRVIIKTEDEKIKRAINTWGEYIREQTLSLSLEINIEIGDNFYSKEYQDLIVGIELNC |
| 1WZ2 Chain:A ((4-866)) | ------------LNFKAIEEKWQKRWLEAKIFEPNIRDKPKEKKFYITVAFPYLSGHLHVGHARTYTIPDVIARFKRMQGYNVLFPMAWHITGSPIVGIAERIKNRDPKTIWIYRDVYKVPEEILWTFEDPINIVKYFMKAAKETFIRAGFSVDWSREFYTTSLFPPFSKFIEWQFWKLKEKGYIVKGAHRVRWDPVVGTPLGDHDLME---GEDVPILDYIIIKFELRENG----EVIYLPAATLRPETVYGVTNMWVNPNATYVKAKVRR----------------------------------------KDKEETWIVSKEAAYKLSFQDR---E-IEVIE-EFKGEKLIGKYVRNPVSG-----DEVIILPAEFVDPDNATGVVMSVPAHAPFDHVALEDLKRETEILEKYDIDPRIV-----FPAVEEVNKLGIKSQKDKEKLEQATKTIYKAEYHKGIFK--VPPYEGKPVQEVKEAIAKEMLEKGIAEIMYEFAEKNVIS-RFGNRAVIKIIHDQWFIDYGNPEWKEKARKALERMKILPETRR-AQFEAIIDWLDKKACARKIGLGTPLPWDPEWVIESLSDSTIYMAYYTISR---------------HINKL---R-Q---EGKLDPEKLTPEFFDYIFLEEFSEDKEKELEKKTGIPAEIIHEMKEEFEYWYPLDWRCSGKDLIPNHLTFFIFNHVAIFREEHWPKGIAVNGFGTL-EGQKMSKSKGNVLNFIDAIEENGADVVRLYIMSLA-EHDSDFDWRRKE--VGKLRK-QIERFYELISQFAEYE----VKG---NVELKDIDRWMLHRLNKAIKETTNALEEFRTRTAVQWAFYSIMNDL-RWYLRRTEG--RD------DEAKRYVLRTLADVWVRLMAPFTPHICEELWEKLGG-EGFVSLAKWPEPVEEWWNETIEAEEEFIRSVMEDIKEIIEVAKIE---NAKRAYIYTAEDWKWKVAEVVSEKRDFKSSMEELMKDSEIRKHGKEVAKIVQKLIKERTFDVKRINEEKALREAKEFMEKELGIEIIINPTEDKGGKKKQAMPLKPAIFIE-------------------------------------------------------------------------------------------------------------------------------------------- |
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General information:
TITO was launched using:
| RESULT:
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Template: 1WZ2.pdb
Alignment : align.pir
Tito was launched with SMD and SCWRL
Tito text output
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3D Compatibility (PKB) -363815 for 6177 contacts (-58.9/contact) +
2D Compatibility (PS) -81164 + (NN) -22827 + (LL) 15444
1D Compatibility (HY) -24000 + (ID) 8150
Total energy: -484512.0 ( -78.44 by residue)
QMean score : 0.363
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