Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTAEKITQGTEGLNVPNEPIIPFIIGDGIGPDIWKAASRVIDAA-VEKAYNGEKRIEWKEVLAGQKAFDT-TGEWLPQETLDTIKEYLIAVKGPLTTPIGGGIRSLNVALRQELDLFTCLRPVRWFKGVPSPVKRPQDVDMVIFRENTEDIYAGIEFKEGTTEVKKVIDFLQNEMGATNIRFPETSGIGIKPVSKEGTERLVRAAIQYAIDNNRKSVTLVHKGNIMKFTEGSFKQWGYDLALSEFGDQVFTWQQYDEIVENEGRDAANAAQEKAEKEGKIIIKDSIADIFLQQILTRPAEHDVVATMNLNGDYISDALAAQVGGIGIAPGANINYETGHAIFEATHGTAPKYAGLNKVNPSSVILSSVLMLEHLGWQEAADKITDSIEDTI-ASKVVTYDFARLMDGAEEVSTSAFADELIKNLK 2D1C Chain:A ((21-355)) -------------------LITVIPGDGIGPECVEATLKVLEAAKAPLAY------EVRE--AGASVFRRGIASGVPQETIESIRKTRVVLKGPLETPVGYGEKSANVTLRKLFETYANVRPVREFPNVPTPYAG-RGIDLVVVRENVEDLYAGIEHMQ-TPSVAQT----------------------LKLISWKGSEKIVRFAFELARAEGRKKVHCATKSNIMKLAEGTLK-----------------------------RAFEQVAQEYPDIEAVHIIVDNAA----HQLVKRPEQFEVIVTTNMNGDILSDLTSGLIGGLGFAPSANIGNEV--AIFEAVHGSAPKYAGKNVINPTAVLLSAVMMLRYLEEFATADLIENALLYTLEEGRVLTGDVVGYDRGAK---TTEYTEAIIQNL-

General information: TITO was launched using: RESULT: Template: 2D1C.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -103596 for 2976 contacts (-34.8/contact) + 2D Compatibility (PS) -36046 + (NN) -7531 + (LL) 4664 1D Compatibility (HY) -24800 + (ID) 7150 Total energy: -174459.0 ( -58.62 by residue) QMean score : 0.487

(partial model without unconserved sides chains): PDB file : Tito_2D1C.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2D1C-query.scw PDB file : Tito_Scwrl_2D1C.pdb: