Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MQKLSEEMKQTIMDIFEHLHANPEVSWKE---YETTSFLKQKLEDLGCRTRTFS-----DCTGVVGEIGS-GSPVVAVRADIDALWQEVNG-------TFRANHSCGH---DSHMTMALGTLMLLKKQPELPKGTIRFIFQPAEEKGG-GALKMIEEGVLDDIDYLYGVHVRPIQETQNGRCAPSILHGSSQHIEGTIIGEEAHGA-RPHLGKNSIEIAAFLVHKLGLIHIDPQIPHTVKMTKLQAGGESSNIIPGKASFSLDLRAQTNEAMEALIAETERACEAAAAAFGAKIELHKEHSLPAATQ---NKEAEAIMAEAITEIIGAERLDDPLVTTGGEDFHFYAV-KVPNLKTTMLGLGCGLQPGLHH-PHMTFDRNAMFTGIHILANAVLKTFQKAESLAAANAS 1CG2 Chain:A ((11-392)) -FQAATDEQPAVIKTLEKLVNIETGTGDAEGIAAAGNFLEAELKNLGFTVTRSKSAGLVVGDNIVGKIKGRGGKNLLLMSHMDTVYLKGILAKAPFRVEGDKAYGPGIADDKGGNAVILHTLKLLKEYGVRDYGTITVLFNTDEEKGSFGSRDLIQEEA-KLADYVLSFEPTS---AGDEK--LSLGTSGIAYVQVNITGKASHAGAAPELGVNALVEASDLVLRTMNIDDK-AKNLRFNWTIAKAGN-VSNIIPASATLNADVRYARNEDFDAAMKTLEERAQQKKL-PEADVKVIVTRGRPAFNAGEGGKKLVDKAVAYYKEAGGTLG--VEERTGGGTDAAYAALSGKPV--IESLGLPG---FGYHSDKAEYVDISAIPRRLYMAARLIMDLGAG----------

General information: TITO was launched using: RESULT: Template: 1CG2.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2026 -121676 -60.06 -341.79 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : -60.06 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.473

(partial model without unconserved sides chains): PDB file : Tito_1CG2.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1CG2-query.scw PDB file : Tito_Scwrl_1CG2.pdb: