Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKFAVIVLPGSNCDIDMYHAVKDELGHEVEYVWHEE--TSLDGFDGVLIPGGFSYGDYLRCGAIARFANIMPAVKQAAAEGKPVLGVCNGFQILQELGLLPGAMRRNKDLKFICRPVELIVQNDETLFTASYEKGESITIPVAHGEGNFYCDDETLATLKENNQIAFTYGSNINGSVSDIAGVVNEKGNVLGMMPHPERAVDELLGSADGLKLFQSIVKNWRETHVTTA 2A9V Chain:A ((15-204)) -KIYVVDNGGQW-THREWRVLREL-GVDTKIVPNDIDSSELDGLDGLVLSGGAPNIDE----ELDKL---GSVGKYIDDHNYPILGICVGAQFIALHF---GASVVKAK-HPEFGKTKVSVM-HSENIFGGLPS--EITVWENHNDEIINLP---------DDFTLAAS--SATC---QVQGFYHKTRPIYATQFHPEVEHTQ-YG----RDIFRNFIGICASYRE---

General information: TITO was launched using: RESULT: Template: 2A9V.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1105 -101463 -91.82 -539.69 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -91.82 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.429

(partial model without unconserved sides chains): PDB file : Tito_2A9V.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2A9V-query.scw PDB file : Tito_Scwrl_2A9V.pdb: