Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKICYVLLSLVCVFLFSGCSAGEEASGKKEDVTLRIAWWGGQPRHDYTTKVIELYEKKNPHVHIEAEFANWDDYWKKLAPMSAAGQLPDVIQM-DTAYLAQYGKKNQLEDLTPYTKDGTIDVSSIDENMLSGGKIDNKLYGFTLGVNVLSVIANEDLLKKAGVSINQENWTWEDYEKLAYDLQEKAGVYGSNGMHPPDIFFPYYLRTKGER-FYKED--G----TGLAYQDDQLFVDYFERQLRLVKAK-TSPTPDESAQIKGMEDDFIVKGKSAITWNYSNQYLGFARLTDSPLSLYLPPEQMQEK--ALTLKPSMLFSIPKSSEHKKEAAKFINFFVNNEEANQLIKGERGVPVSDKVADAIKPKLNEEETNIVE-YVETASKNISKADPPEPVGSAEVIKLLKDTSDQILYQKV-SPEKAAKTFRKKANEILERNN 2GH9 Chain:A ((2-379)) ---------------------------------KITVWTHFGGPELEWLKEQARTFERT-SGTKVEVVEVPFAEIKQKFILGAPQGQAADLVVTVPHDWVGEMAQAGVLEPVGKYVTQ--AYLADLQGVAVEAFTFGGRLMGLPAFAESVALIYNKKYVKE----PP---RTWEEFLALAQKLTTG-ATFGFLYNIGDPYFNFGFFKAFGAENVFAKDAKGNLDPTKLLIGGE-VGEKALQFIKDLRFKYNLVPEG-V--DY-GVADGAFKDGALAMILNGPWALGDYKKA-KVDFGIAPFPVPPGAKNPWGPFLGVQGVVVNAYSKNKTQAVNFAKTLVTGRNLVAFNQAGGRIPVSKSAVKQLEK------DPVVAGFSKVF-PL-G-APMPNIPEMGKVWGPWGNAISLAIQRPDSNVKKIVEDMVAEIKKAIG---

General information: TITO was launched using: RESULT: Template: 2GH9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2043 -195058 -95.48 -534.40 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : -95.48 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.447

(partial model without unconserved sides chains): PDB file : Tito_2GH9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2GH9-query.scw PDB file : Tito_Scwrl_2GH9.pdb: