Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGQSFNAPYEAIG-EELLSQLVDTFYERVASHPLLKPIFP-SDLTETARKQKQFLTQYLGGPPLYTEEHGHPMLRARHLPFPITNERADAWLSCMKDA---MDHVGLEGEIREFLFGRLELTARHMVNQTEAEDRSS 2QRW Chain:B ((2-125)) -PKSF---YDAVGGAKTFDAIVSRFYAQVAEDEVLRRVYPEDDLAGAEERLRMFLEQYWGGPRTYSEQRGHPRLRMRHAPFRISLIERDAFLRCMHTAVASIDSETLDDEHRRELLDYLEMAAHSLVN---------

General information: TITO was launched using: RESULT: Template: 2QRW.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 401 -61347 -152.98 -515.52 target 2D structure prediction score : 0.83 Monomeric hydrophicity matching model chain B : 0.79 3D Compatibility (PKB) : -152.98 2D Compatibility (Sec. Struct. Predict.) : 0.83 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.652

(partial model without unconserved sides chains): PDB file : Tito_2QRW.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2QRW-query.scw PDB file : Tito_Scwrl_2QRW.pdb: