Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSKIYVLDTNVLLQDPNAIFSFEENEVVIPAVVLEEVDSKKRYMDEVGRNARHVSKLIDALRQKGRLHEHVPLDTGGTLRIELNHRSFHQLQEIFIEKTNDNRILAVAKNLSLEEETKENGRPVILVSKDVLVRVKADAIGLLAEDFLNDRVVDNDEMYSGYKDLYISQQLFSSFYGKNQISVNDVKQHAFYPNQFALMKDELGGSSSAVGIADKTGTVLKRLVFDDEHIWGIRPKNVQQTMALELLLREDIPLVTLIGKAGTGKTLL-ALAAGLLQTED-LGIYKKLVVARPIV-PVGKDIGYLPGEKEEKLKPWMQPIFDNLEFLFNAKKPG------------------------E---LDAILAGIGSIQVEALTYIRGRSIPDQFIIIDEA-QNLTRHEVKTLLTRVG-----EGSKIVL-MGDPEQIDHPYLDSLNNGLAYVVERFKGQPISGSVKLLKGERSGLAQLAADLL 4MYC Chain:A ((461-636)) ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AGWKTAIVGSSGSGKSTILKLVFRFYDPESGRILINGRDIKEYDIDALRKVIGVVPQDT--PL--FNDTIWENVKFGRIDATDEEVITVVEKAQLAPLIKKLPQGFDTIVGERGL-MISGGEK--QRLAIARVLLKNARIMFFDEATSALDTHTEQALLRTIRDNFTSGSRTSVYIAHRLRTI----------------------------------------------

General information: TITO was launched using: RESULT: Template: 4MYC.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 498 -43812 -87.97 -315.19 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain A : 0.57 3D Compatibility (PKB) : -87.97 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.57 QMean score : 0.372

(partial model without unconserved sides chains): PDB file : Tito_4MYC.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4MYC-query.scw PDB file : Tito_Scwrl_4MYC.pdb: