Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSMAYEEYMRQLVVPMRRELTGAGFEELTTAEEVENFMEKAEGTTLVVVNSVCGCAAGLARPAATQAVLQNDKTPDNTVTVFAGQDKEATAKMREYFTGQEPSSPSMALLKGKEVVHF-IPRHEIEGHDMEEIMKNLTAAFDAHC 2BHO Chain:A ((3-112)) --TTFTELMQQLFLKL-------GLNHQVNENDVYTFEVDGHIQVLIACY------------------------HQQWVQLFSELGADLPT--NDNLFGEHWPAHVQGRLDGKPILWSQQSLVGLDIDEMQAWLERFIDDIEQRK

General information: TITO was launched using: RESULT: Template: 2BHO.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 404 -23397 -57.91 -214.65 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : -57.91 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.433

(partial model without unconserved sides chains): PDB file : Tito_2BHO.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2BHO-query.scw PDB file : Tito_Scwrl_2BHO.pdb: