Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGSMDQSIAVKSPLTYAEALANTIMNTYT-VEELPPANRWHYHQGVFLCGVLRLWEATGEKRYFEYAKAYADLLIDDNGNLLFRRDELDAIQAGLILFPLYEQTKDERYVKAAKRLRSLYGTLNRTSEGGF--WHKDGYPYQMWLD--GLYMGGPFALKYANLKQETELFDQVVLQESLMRKHTKDAKTGLFYHAW---DEAKKMPWANEETGCSPEFWARSIGWYVMSLADMIEELPKKHPNRHVWKNTLQDMIKSICRYQDKETGLWYQIVDKGDRSDNWLESSGSCLYMYAIAKGI----NKGYLDRAYETTLLKAYQGLIQHKTETSEDGAF-LVKDICVGTSAGFYDYYVSRERSTNDLHGAGAFILAMTELEPLFR----SAGK 1VD5 Chain:A ((1-377)) MWQQAIGDALGITARNLKKFGDRFPHVSDGSNKYVLNDNTDWTDGFWSGILWLCYEYTGDEQYREGAVRTVASFRERLDRFENLDHHDIGFLYSLSAKAQWIVEKDESARKLALDAADVLMRRWRADAGIIQAWGPKGDPENGGRIIIDCLLNLPLLLWAGEQTGDPEYRRVAEAHALKSRRFLVRGDDSSYHTFYFDPENGNAIRGGTHQGNTDGSTWTRGQAWGIYGFALNSRYL-----GNADLLETAKRMARHFLARV-PEDGVVYWDFEVPQEPSSYRDSSASAITACGLLEIASQLDESDPERQRFIDAAKTTVTALRDGYAERDDGEAEGFIRRGSYHVRGG-------ISPDDYTIWGDYYYLEALLRLERGVTGYWYERGR

General information: TITO was launched using: RESULT: Template: 1VD5.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2151 41556 19.32 115.43 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : 19.32 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.477

(partial model without unconserved sides chains): PDB file : Tito_1VD5.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1VD5-query.scw PDB file : Tito_Scwrl_1VD5.pdb: