Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSGQMFKVEIVTRPANFEKLKQELGKIGVTSLTFSNVHGCGLQKAHTELYRGVKIESNVYERLKIEIVVSKVPVDQVTETAKRVLKTGSPGDGKIFVYEISNTINIRTGEEGPEAL 2XZW Chain:D ((1-112)) ----MKKIEAIIRPFKLDEVKIALVNAGIVGMTVSEVRGFGRQKG----------TVEFLQKLKLEIVVEDAQVDTVIDKIVAAARTGEIGDGKIFVSPVDQTIRIRTGEKNADAI

General information: TITO was launched using: RESULT: Template: 2XZW.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain D - contact count / total energy / energy per contact / energy per residue : 384 -48485 -126.26 -475.34 target 2D structure prediction score : 0.78 Monomeric hydrophicity matching model chain D : 0.79 3D Compatibility (PKB) : -126.26 2D Compatibility (Sec. Struct. Predict.) : 0.78 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.470

(partial model without unconserved sides chains): PDB file : Tito_2XZW.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2XZW-query.scw PDB file : Tito_Scwrl_2XZW.pdb: