Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTILEIKDLHVSVENPAEADHEIPILRGVDLTVKSGETHALMGPNGSGKSTLSYAIAGHPKYH--VTSGTITLDGADVLAMSIDE---RARAGLFLAMQYPV--EVPGVSMSNFLRSAATAIRGEPPKLRHWVKEVKAAMAALDIDP-AFAERSVNEGFSGGEKKRHEILQLELLKPKIAILDETDSGLDVDALRVVSEGVNRYAESQHGGILLITHYTRILRYIHPEYVHVFVGGRIVESGGSELADELDQNGYVRFSPASGRYPHQPAPTGA 4FWI Chain:B ((3-254)) -IIIRVEDLRAVYLVR---EGTIKAADGISLDILENSVTAIVGESASGKSTIIEAMTKTLPPNGRILSGRVLYKGKDLLTMREEELRKIRWKEIALVPQAAQQSLNPTMKVIEHFKDTVEAHGV-RWSHSELIEKASEKLRMVRLNPEAVLNSYP-LQLSGGMKQRVLIALALLLDPVVLILDEPTSALDVLTQAHIIQLLKELKKMLKITLIFVTHDIAVAAEL-ADKVAVIYGGNLVEYNSTFQIFK-------------------------

General information: TITO was launched using: RESULT: Template: 4FWI.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -118007 for 1834 contacts (-64.3/contact) + 2D Compatibility (PS) -25548 + (NN) -10586 + (LL) 1032 1D Compatibility (HY) -11600 + (ID) 2600 Total energy: -167309.0 ( -91.23 by residue) QMean score : 0.508

(partial model without unconserved sides chains): PDB file : Tito_4FWI.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4FWI-query.scw PDB file : Tito_Scwrl_4FWI.pdb: