Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTKKRITFGLLVLMVCVILFVLYVQLRNKDSIPVQSSAIHPEEDRIFFIYSNPFIKESVLLSTSTGERFNRRTFKVADVPYIQTKSYASTDLVLLAEHEPFYYTLEKDVIKEHPLSDPFAFWYEGKDVTIEAYNVDTTGNEIHINDRKTKKEYTLTLPPLVTMGASDENFIYIIQSM---SIYVIDRKTEEMIETLSL-ASYADQFADSE--EFIVASS-DHKLTVIEKGTWKT-TYIAYPED--LEYADTVYYDKESGSFYVAYEDKEGGANLLEYGEDF-SI-HTYSLKFPYMEAKF--KGNLLYIVAQEEHKKGIGGYVGVFDIHSKEMLYQFDLPEEQVKVQDFVVVDNK 3VGZ Chain:A ((148-315)) -------------------------------------------------------------------------------------------------------------------------------------------------------------------ADDATNTVYISGIGKESVIWVVDGGNIKLKTAIQNTGKMSTGLALDSEGKRLYTTNADGELITIDTADNKILSRKKLLDDGKEHFFINISLDTARQRAFITDSKA---AEVLVVDTRNGNILAKVAAPE-SLAVLFNPARNEAYVTHR------QAGKVSVIDAKSYKVVKTFDTPTH-------------

General information: TITO was launched using: RESULT: Template: 3VGZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 783 -82394 -105.23 -535.02 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain A : 0.57 3D Compatibility (PKB) : -105.23 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.57 QMean score : 0.452

(partial model without unconserved sides chains): PDB file : Tito_3VGZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3VGZ-query.scw PDB file : Tito_Scwrl_3VGZ.pdb: