Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKVNGIHHVSALTADAQKNLDFYKKVLGLKLVKKSVNQDEPTMYHLFYGDEVANPGTELTFFEIPRIAPFHAGTNSISSIGLRVPGTEALHYWKERFEEQQVTHSGI-S---KRAGRDILAFQDHEGQRLVLTADEEGKGYGLPVKQSGIPEEFSFRGLGPVELTVPYAEPTLHVLTNILGFTEISREPVEGQGTAVILESGEGGAATEIHLIERNDLPRERQGKGSVHHVAFRVRDEEELAGWHRIISREGFSNSG-IVER--YYFKALYFREPNGILFELSTDGPGFMVDENLDELGQTIALPPYLEHRRAEIEAKLKPIQ 3B59 Chain:A ((4-260)) SRVTEIRYVGYGVKDFDAEKAFYADVWGLEPVGEDANN-------AWFKAQG---ADEHHVVQLRR-----ADENRIDVIALAADSRSDVDALRASVEAAGCKVASEPAVLATPGGGYGFRFFSPDGLLFEVSSDVAKGAK-RD--LA--RWEGVPVKISHIVLHSPNHQDMVKFFTDVLGFKVSDWLGD----FMCFLRCN--SAHHRIAILPG---------PPCLNHVAYDMLSVDDMMRGAHRLKVKGIDIGWGPGRHTAGNNTFSYFVTPGGFVTEYTSELEEVDFD-------------------------------

General information: TITO was launched using: RESULT: Template: 3B59.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1460 -126198 -86.44 -504.79 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -86.44 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.553

(partial model without unconserved sides chains): PDB file : Tito_3B59.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3B59-query.scw PDB file : Tito_Scwrl_3B59.pdb: