Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRKTDRHPVSGANSLWHVYQTVPFLKVVKNFIVIQIARYTPFIGMKNWLYRTFLRMKVGKQTSFALMVMPDIMFPEKISVGTNTIIGYNTTILAHEYLIH-------EYRIGKVLIGDEVMIGANTTILPGVKIGDGAVVSAGTLVHKDVPDGAFVGGNPMRIIYTKEEMQERLKKSAE 1KRR Chain:B ((84-190)) -------------------------------------------------------------ANFNLTIVDDYT----VTIGDNVLIAPNVTLSVTGHPVHHELRKNGEMYSFPITIGNNVWIGSHVVINPGVTIGDNSVIGAGSIVTKDIPPNVVAAGVPCRVI---REINDRDK----

General information: TITO was launched using: RESULT: Template: 1KRR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 486 -28927 -59.52 -289.27 target 2D structure prediction score : 0.39 Monomeric hydrophicity matching model chain B : 0.67 3D Compatibility (PKB) : -59.52 2D Compatibility (Sec. Struct. Predict.) : 0.39 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.411

(partial model without unconserved sides chains): PDB file : Tito_1KRR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1KRR-query.scw PDB file : Tito_Scwrl_1KRR.pdb: