Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEDYIKIEKIGEGTYGVVYKGRHRVTGQIVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQFMDSSLVKSYLHQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKN-TFPKWKPGSLASHVKNLDENGLDLLSKMLVYDPAKRISGKMALKHPYFDDLDNQIKKM 3NIZ Chain:A ((20-310)) MEKYQKLEKVGEGTYGVVYKAKD-SQGRIVALKRIR------GIPSTAIREISLLKELHHPNIVSLIDVIHSERCLTLVFEFMEKDLKKVLDENK--TGLQDSQIKIYLYQLLRGVAHCHQHRILHRDLKPQNLLINSDGALKLADFGLARAFGIPVR---HEVVTLWYRAPDVLMGSKKYSTSVDIWSIGCIFAEMITGKPLFPGVTDDDQLPKIFSILGTPNPREWPQVQELPLWKQRTFQVFEKKPWSSIIPGFCQEGIDLLSNMLCFDPNKRISARDAMNHPYFKDLDPQ----

General information: TITO was launched using: RESULT: Template: 3NIZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -160415 for 2193 contacts (-73.1/contact) + 2D Compatibility (PS) -29427 + (NN) -11523 + (LL) 1228 1D Compatibility (HY) -32800 + (ID) 8500 Total energy: -241437.0 ( -110.09 by residue) QMean score : 0.483

(partial model without unconserved sides chains): PDB file : Tito_3NIZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3NIZ-query.scw PDB file : Tito_Scwrl_3NIZ.pdb: