Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLGITVLAALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLK-NDTWRHTCGGTLIASNFVLTAAHCISN---TRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALL--LRNDIALIKLAEH----VELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNG-PIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQL 3MHW Chain:U ((1-246)) -----------------------------IIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLGRSRLNS-NTQGEMKFEVENLILHKDYSAD-LAHHNDIALLKIRSKEGRCAQPSRTIQTISLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKMLCAADPQWKTDSCQGDSGGPLVCS-LQGRMTLTGIVSWGR--GCALKDKPGVYTRVSHFLPWIRSHTK-

General information: TITO was launched using: RESULT: Template: 3MHW.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -170641 for 2005 contacts (-85.1/contact) + 2D Compatibility (PS) -25156 + (NN) -8327 + (LL) 2668 1D Compatibility (HY) -14000 + (ID) 3700 Total energy: -219156.0 ( -109.30 by residue) QMean score : 0.428

(partial model without unconserved sides chains): PDB file : Tito_3MHW.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3MHW-query.scw PDB file : Tito_Scwrl_3MHW.pdb: