Modeling by threading (Tito software)
Unconserved sides chains calculation (Scwrl software)
Evaluation (QMean software)
Input alignment information:
| Query sequence | MKPKHYPDTISSPDFSSLEKEIIKFWQENKIFEQSVEKRSKDNCFVFYDGPPFANGLPHYGHLLTGFIKDAFARYQTMLQKKVERRFGWDCHGLPAEMGAEKELGISGRT---EIEKFGIEKF----NNYCRTSVMKFSSEWEKYVNRQARWVDFHNDYKTMD--RSFMESVIWAFKQLYDKGLVYESVRVVPYSWACETPLSNFETRLDTAYRKK--TSKAVTVAFELLENPQQFKQKCKLLAWTTTPWTLPSNLALAIGKDIEYCAVSVHSSVSFQHVTLESREKETWIPLSRTGMTEEGTETVTEDNEVSLVNNEIYIFAEDYLEKFIGHCEQNNIPYENCNTKLKADDLAGLSYKPLFNYFKGTKNAFRVFIADYVTGEDGTGVVHTAPGFGEEDFY----------LCQSHDIPAI------CPIDNSGRFTA-----------------------EVSDLTGIHVFDTNDAIIKKLKEQGNWFKTEQYIHNYPHCWRTDTPLIYRAMPSWYVAVT--KFKERMIELNKRVNWIPTHIRDGQFGKWLERAHDWSISRNRFWGTPIPI---WKSDNARYPR--VDVY-----GSIAELERDFNVKVNDLHRPFIDSLTRPNPDDPTGKSIMRRVPDVFDCWFESGSVPFAQ------VHYPFE----NKEWFESNFPADFITEYIAQTRGWFYTLFVLSTALF-DSEPFKNCICHGVVLDVKGQKLSKRLNNYADPMEVFDKYGSDALRFLMLSGSIVCGGNLFLNKEGSSIRDVLKNVMKPIWNSYHFFTMYANADGIKAEVCKDYKSTIDSYMIFKCFEAVESIQASMSNYNSQEACKILID-FFEVLNNWYIRRSRERFWKSNLDQDKTDAYNVLYTVFYYILRAAVPLLPLITETIWQGLKYKEISVHLADFPQLERYDSELIAKMDLVREICNSALSIRNTFNIRVRQPLGSMTVYHQSSCSFLESKPLSVVIPKFSPVIPMRDTGTQKEKKWSNAEMKTSMNEYQEMIKDEVNVKELKLVNSLEGIASLELKLNFPMLGKRIPDKVKKLVQYVKEGKWKQVDNEQVFLGNESESYIIEKDEYELLLKTNSEYSSVFGDNKGIVILNTALDDALVLEGLARDVVRLIQEARKQADFHISDRIRVIIKTEDEKIKRAINTWGEYIREQTLSLSLEINIEIGDNFYSKEYQDLIVGIELNC |
| 1WKB Chain:A ((4-810)) | ------------LNFKAIEEKWQKRWLEAKIFEPNIRDKPKEKKFYITVAFPYLSGHLHVGHARTYTIPDVIARFKRMQGYNVLFPMAWHITGSPIVGIAERIKNRDPKTIWIYRDVYKVPEEILWTFEDPINIVKYFMKAAKETFIRAGFSVDWSREFYTTSLFPPFSKFIEWQFWKLKEKGYIVKGAHRVRWDPVVGTPLGDHDL----MEGEDVPILDYIIIKFELRENG----EVIYLPAATLRPETVYGVTNMWVNPNATYVKAKVRR----------------------------------------KDKEETWIVSKEAAYKLSFQDR---E-IEVIE-EFKGEKLIGKYVRNPVSG-----DEVIILPAEFVDPDNATGVVMSVPAHAPFDHVALEDLKRETEILEKYDIDPRIVFPAVEEVNKLGIKSQKDKEKLEQATKTIYKAEYHKGIFKVPPYEGKPVQEVKEAIAKEMLEKGIAEIMYEFAEKNVISRFGNRAVIKIIHDQWFIDYGNPEWKEKARKALERMKILPETRR-AQFEAIIDWLDKKACARKIGLGTPLPWDPEWVIE--SLSDSTIYMAYYTISRHINKLRQE-GK----------------------LD-PEKLTPEFFDYIFLEEFSEDKEKELEKKTGIPAEIIHEMKEEFEYWYPLDWRCSGKDLIPNHLTFFIFNHVAIFREEHWPKGIAVNGFGTL-EGQKMSKSKGNVLNFIDAIEENGADVVRLYIMSLA-EHDSDFDWRRKE--VGKLRK-QIERFYELISQFAEYEV----KG---NVELKDIDRWMLHRLNKAIKETTNALEEFRTRTAVQWAFYSIMNDL-RWYLRRTEG--RD------DEAKRYVLRTLADVWVRLMAPFTPHICEELWEKLG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- |
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General information:
TITO was launched using:
| RESULT:
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Template: 1WKB.pdb
Alignment : align.pir
Tito was launched with SMD and SCWRL
Tito text output
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3D Compatibility (PKB) -334141 for 5816 contacts (-57.5/contact) +
2D Compatibility (PS) -76028 + (NN) -21047 + (LL) 27912
1D Compatibility (HY) -21200 + (ID) 7500
Total energy: -432004.0 ( -74.28 by residue)
QMean score : 0.367
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