Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNEERYSTKRITVKEIDEILYEEHRVLDHGFIRVVDYMGSDSAIVQAARVSYGKGTKQINQDEVLIKYLMRYHHTTPFEMCEIKFHVKLPIFIARQWIRHRTANVNEYSARYSILDHEFYIPEPEQVAKQSDNNKQGSGEAFDLDISKEIIDSLIND-SNLVYSHYNKFIEQGLTREIARTNLTLNYYTQFYWKVDLHNLLHFLKLRADKRAQHEIRVYAEVILDIVKKWVPLVHSAFVEYCLESACISRTGLGIIRKLIRGENVTREESNIGKREWEELMFILDKQPER 4KAT Chain:D ((17-221)) -------------------------ILDKGFVELVDVMGNDLSAVRAARVSF------EERDRHLIEYLMKHGHETPFEHIVFTFHVKAPIFVARQWFRHRIASYNELSGRY----YEFYIPSPERL------------EGYKTTIPPERVTEKISEIVDKAYRTYLELIESGVPREVARIVLPLNLYTRFFWTVNARSLMNFLNLKADSHAQWEIQQYALAIARIFKEKCPWTFEAFLKYAYKGDILKEV---------------------------------------

General information: TITO was launched using: RESULT: Template: 4KAT.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -161517 for 1433 contacts (-112.7/contact) + 2D Compatibility (PS) -20182 + (NN) -352 + (LL) 5504 1D Compatibility (HY) -19200 + (ID) 4650 Total energy: -200397.0 ( -139.84 by residue) QMean score : 0.384

(partial model without unconserved sides chains): PDB file : Tito_4KAT.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4KAT-query.scw PDB file : Tito_Scwrl_4KAT.pdb: