Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKVMLATALFLGLTPAGANAADLGHQTLGSNDGWGAYSTGTTGGSKASSSNVYTVSNRNQLVSALGKET-----NTTPKIIYIKGTIDMNVDDNLKPLGLNDYKDPEYDLDKYLKAYDPSTWGKKEPSGTQEEARARSQKNQKARVMVDIPANTTIVGSGTNAKVVGGNFQIK-SDNVIIRNIEFQDAYDYFPQWDPTDGSSGNWNSQYDNITINGGTHIWIDHCTFNDGSRPDSTSPKYYGRKYQHHDGQTDASNGANYITMSYNYYHDHDKSSIFGSSDSKTSDDGKLKITLHHNRYKNIVQRAPRVRFGQVHVYNNYYEGSTSSSSYPFSYAWGIGKSSKIYAQNNVIDVPGL-SAAKTISVFS-GGTALYDSGTLL--------NGTQI--NASAANGLSSSVGWTPSLHGSIDASANVKSNVINQAGAGKLN 1VBL Chain:A ((4-416)) ------------------------GHEVLKPYDGWAAYGEGTTGGAMASPQNVFVVTNRTELIQALGGNNHTNQYNSVPKIIYVKGTIDLNVDDNNQPVGPDFYKDPHFDFEAYLREYDPATWGKKEVEGPLEEARVRSQKKQKDRIMVYVGSNTSIIGVGKDAKIKGGGFLIKNVDNVIIRNIEFEAPLDYFPEWDPTDGTLGEWNSEYDSISIEGSSHIWIDHNTFTDGDHPDRSLGTYFGRPFQQHDGALDIKNSSDFITISYNVFTNHDKVTLIGASDSRMADSGHLRVTLHHNYYKNVTQRLPRVRFGQVHIYNNYYEFSNLAD-YDFQYAWGVGVFSQIYAQNNYFSFDWDIDPSLIIKVWSKNEESMYETGTIVDLPNGRRYIDLVASYNESNTLQLKKEVTWKPMFYHVIHPTPSVPALVKAKAGAGNLH

General information: TITO was launched using: RESULT: Template: 1VBL.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2529 -83763 -33.12 -212.06 target 2D structure prediction score : 0.74 Monomeric hydrophicity matching model chain A : 0.83 3D Compatibility (PKB) : -33.12 2D Compatibility (Sec. Struct. Predict.) : 0.74 1D Compatibility (Hydrophobicity) : 0.83 QMean score : 0.675

(partial model without unconserved sides chains): PDB file : Tito_1VBL.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1VBL-query.scw PDB file : Tito_Scwrl_1VBL.pdb: