Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence --------------------------------------------------------------------------MKHKVIVNHWEEICEDDSCYEYGTSIIVNGKELIREASIITALKA-VLEEIGADVEIEETVESEKCCDSLRKKNLDY------------------------------------------------------- 2DG5 Chain:B ((1-190)) TTHYSVVDKDGNAVAVTYTLNTTFGTGIVAGESGILLNNQMDDFSAKPGVPNVYGLVGGDANAVGPNKRPLSSMSPTIVVKD--------------GKTWLVTGSP--GGSRIITTVLQMVVNSIDYGLNVAEATNAPRFHHQWLPDELRVEKGFSPDTLKLLEAKGQKVALKEAMGSTQSIMVGPDGELYGASDPRSVDDLTAGY

General information: TITO was launched using: RESULT: Template: 2DG5.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 159 -2502 -15.73 -41.69 target 2D structure prediction score : 0.38 Monomeric hydrophicity matching model chain B : 0.57 3D Compatibility (PKB) : -15.73 2D Compatibility (Sec. Struct. Predict.) : 0.38 1D Compatibility (Hydrophobicity) : 0.57 QMean score : 0.336

(partial model without unconserved sides chains): PDB file : Tito_2DG5.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2DG5-query.scw PDB file : Tito_Scwrl_2DG5.pdb: