Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MWRNASMNHSKRNDANDFDSMDEWLRQFFEDPFAWYDETLPIDLYETSQQYIIEADLTFLQPTQVTVTLSGCEFILTVKSS---------GQTFEKQMMLPFYFNDKNIQVECE-NQILTVAVNKETEDGSSFSLQFPLS 4MJH Chain:A ((2-87)) ----------------------------------------VSEIRHTADRWRVSLDVNHFAPDELTVKTKDGVVEITGKHEERQDEHGYISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEAPMP--------------

General information: TITO was launched using: RESULT: Template: 4MJH.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 218 -19587 -89.85 -257.72 target 2D structure prediction score : 0.72 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -89.85 2D Compatibility (Sec. Struct. Predict.) : 0.72 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.545

(partial model without unconserved sides chains): PDB file : Tito_4MJH.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4MJH-query.scw PDB file : Tito_Scwrl_4MJH.pdb: