Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSNIISKEQDEAIKYFRNKLNLSDKDLYIPLINFELLRDKNEQYANILYELYKNDPYLFIRALKEGYVVNQPIAFDEAIVRFFNGEELAIVHKTTGRRYNVNVKMKQLPDGFSLQTMDMWLWSELV 4OM3 Chain:A ((10-126)) -----KFTIPESLDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMYYEMSYGLNIEMHKQTEIAKRLNTICAQVIPFLSQEHQQQVAQAVERAKQVT--MAELNAIIGQQQLQAQHLSH--

General information: TITO was launched using: RESULT: Template: 4OM3.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 57 -8093 -141.98 -69.17 target 2D structure prediction score : 0.44 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -141.98 2D Compatibility (Sec. Struct. Predict.) : 0.44 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.084

(partial model without unconserved sides chains): PDB file : Tito_4OM3.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4OM3-query.scw PDB file : Tito_Scwrl_4OM3.pdb: